化工社化工社 化学情報印刷レポート · 研究参考用
5-Bromo-6-chloropyridine-3-carboxylic acid → 5-bromo-6-chloro-N-(3-fluoro-4-((trifluoromethyl)thio)phenyl)nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| 反応物 | 3-Fluoro-4-[(trifluoromethyl)sulfanyl]aniline | HCID 21614381 | — |
| 生成物 | 5-bromo-6-chloro-N-(3-fluoro-4-((trifluoromethyl)thio)phenyl)nicotinamide | HCID 86702611 | — |
反応手順
The title compound was prepared in an analogous fashion to that described in Stage 11.2 using 5-bromo-6-chloro-nicotinic acid and 3-fluoro-4-trifluoromethylsulfanyl-aniline to afford a white crystalline solid. HPLC (Condition 4) tR=6.71 min, UPLC-MS (Condition 3) tR1.34 min, m/z=429 [M−H]−.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08829195B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-af3ce584787342338c318f4976c8e16e |
| 出典メモ | uspto-grants-2014_09 |