化工社化工社 化学情報印刷レポート · 研究参考用
3-Methyl-2-thenoyl Chloride → 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methyl-2-thenoyl Chloride | HCID 2737605 | — |
| 反応物 | Methyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 22645079 | — |
| 生成物 | 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester | HCID 32468521 | 47% |
反応手順
581 mg (3 mmol) of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid phenylmethyl ester, and 482 mg (3 mmol) of 3-methyl-2-thiophenecarbonyl chloride was used instead of phenylacetyl chloride in the process according to Reference Example 1 to obtain 394 mg (47%) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08829209B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-115d9aa10ec54874a1d6b746c5951c72 |
| 出典メモ | uspto-grants-2014_09 |