化工社化工社 化学情報印刷レポート · 研究参考用
Leucine, N-carboxy-, N-benzyl ester, L- → N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Leucine, N-carboxy-, N-benzyl ester, L- | HCID 74840 | — |
| 反応物 | (2S)-2-Amino-1-hexanol | HCID 5494388 | — |
| 生成物 | N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol | HCID 15168139 | 58% |
反応手順
N-[(phenylmethoxy)carbonyl]-L-leucine was used instead of 1-[[(phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid, and L-norleucinol was used instead of L-valinol in the process according to Reference Example 178 to obtain 421 mg (58%) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08829209B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-ac37e11a459a4ff08d4c2ee4c1c96d22 |
| 出典メモ | uspto-grants-2014_09 |