Acetic acid, 2-oxo-, methyl ester → methyl (2E)-2-[(2-chlorophenyl)hydrazinylidene]acetate
反応式
[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=O.Cl.[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15][NH2:16]>CO>[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15]/[N:16]=[CH:2]/[C:1]([O:5][CH3:6])=[O:4]参加物
4
実験手順
To a solution of methyl glyoxylate (6.8 g, 77 mmol) in methanol (150 mL) was added 2-chlorophenylhydrazine hydrochloride (12.5 g, 77 mmol) and the mixture was heated at reflux overnight, cooled and concentrated. The residue was re-dissolved in toluene and concentrated to give the title compound of Step A.
後処理
- temperaturethe mixture was heated
- temperatureat reflux overnight
- temperaturecooled
- concentrationconcentrated
- dissolutionThe residue was re-dissolved in toluene
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-a1a53def4c664a96999097c0e8311779
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07087598B2
反応ノート
読み込み中…