化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 3-(2,4-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 1-Isothiocyanato-2,4-dimethylbenzene | HCID 142386 | — |
| 反応物 | N-Ethylglycine | HCID 316542 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 3-(2,4-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-one | HCID 11402401 | 43.6% |
反応手順
The title compound was prepared by the procedure described in Example 16 using 16.3 g of 2,4-dimethylphenyl-isothiocyanate, 18.4 g of N-ethyl glycine, 20.2 g of triethyl amine, and 250 mL of chloroform. Crystallization from ethanol afforded the title compound (10.8 g) as a light peach solid, m.p. 161°-162° C. Anal. Calcd. for. C13H16N2O S: C,62.87; H, 6.49; N, 11.28. Found: C, 62.63; H, 6.45; N, 11.17. Mass spectrum (El, M.+) m/z 248.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05554607 |
| 出典データセット | uspto-grants-1996_09 |
| ORD ID | ord-c23a548dbd0c42f8a6d64950860143bc |
| 出典メモ | uspto-grants-1996_09 |