HCID 21473739、化合物 → HCID 10107954、化合物
反応式
[CH2:1]([O:3][C:4](/[CH:6]=[CH:7]/[C:8]1[S:12][C:11]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])=[CH:10][CH:9]=1)=[O:5])[CH3:2]>C(O)C.[C].[Pd]>[CH2:1]([O:3][C:4]([CH2:6][CH2:7][C:8]1[S:12][C:11]([C:13]([O:15][C:16]([CH3:17])([CH3:19])[CH3:18])=[O:14])=[CH:10][CH:9]=1)=[O:5])[CH3:2]参加物
4
実験手順
The t-butyl 5-(2-ethoxycarbonyl-E-ethenyl)-2-thiophenecarboxylate (7.58 g, 26.8 mmol) prepared in the Preparative Example 14 was catalytically reduced with 10% palladium-carbon (1.05 g) in ethanol at room temperature. After the completion of the reaction, the catalyst was filtered out and the filtrate was concentrated and evaporated to dryness in a vacuum. 7.6 g of the title compound was obtained.
後処理
- customAfter the completion of the reaction
- filtrationthe catalyst was filtered out
- concentrationthe filtrate was concentrated
- customevaporated to dryness in a vacuum
出典と根拠
- ORDレコード
- ord-c766c541f0c84f15a9a7c60cc344d910
- 出典データセット
- uspto-grants-1996_09
- 特許番号
- US05554615
反応ノート
読み込み中…