Acetic Acid → Isobutyl 2-acetyloxy-5-[2(4-sulfophenyl)ethenyl]benzoate potassium salt

HRID 743013ノート

反応式

HRID 743013 の反応式
[K:1].[K].[OH:3][C:4]1[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]2[CH:24]=[CH:23][C:22]([S:25]([OH:28])(=[O:27])=[O:26])=[CH:21][CH:20]=2)=[CH:13][C:5]=1[C:6]([O:8][CH2:9][CH:10]([CH3:12])[CH3:11])=[O:7].[C:29](O)(=[O:31])[CH3:30].C(OC(=O)C)(=O)C.S(=O)(=O)(O)O>C(OCC)C>[K:1].[C:29]([O:3][C:4]1[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]2[CH:20]=[CH:21][C:22]([S:25]([OH:28])(=[O:26])=[O:27])=[CH:23][CH:24]=2)=[CH:13][C:5]=1[C:6]([O:8][CH2:9][CH:10]([CH3:12])[CH3:11])=[O:7])(=[O:31])[CH3:30]

参加物

6

反応物 4

HCID 176Acetic AcidHCID 1118Sulfuric AcidHCID 7918Acetic Anhydride2 回HCID 86747766Isobutyl 2-hydroxy-5-[2-(4-sulfophenyl)ethenyl]benzoate dipotassium salt

生成物 1

HCID 86747765Isobutyl 2-acetyloxy-5-[2(4-sulfophenyl)ethenyl]benzoate potassium salt

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

Isobutyl 2-hydroxy-5-[2-(4-sulfophenyl)ethenyl]benzoate dipotassium salt (37.2 g, 0.09 mol) was added to a boiling solution of acetic acid (20 ml) and acetic anhydride (80ml). Sulfuric acid (8 ml) was added cautiously and the mixture refluxed until the major part of the solids had dissolved, and then more acetic anhydride (80 ml) was added. After boiling for 1 h, the mixture was cooled to room temperature. Diethyl ether (350 ml) was added and the suspension filtered and washed with diethyl ether. Yield 36.1 g (88%)

後処理

  1. temperaturethe mixture refluxed until the major part of the solids
  2. dissolutionhad dissolved
  3. filtrationthe suspension filtered
  4. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-5707781749cb4b4c9d6939c74186559e
出典データセット
uspto-grants-1996_09
特許番号
US05556855

反応ノート

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