Hydrochloric Acid → HCID 57497648、化合物

反応式

[CH3:1][N:2]([CH2:4][CH:5]([OH:25])[CH2:6][O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:3].[ClH:26]>C(OCC)(=O)C.O1CCOCC1>[ClH:26].[CH3:1][N:2]([CH2:4][CH:5]([OH:25])[CH2:6][O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)[CH3:3]

参加物

実験手順

0.225 g of 3-(N,N-dimethylamino)-1-[2-(5-phenylpentyl)phenoxy]-2-propanol [prepared as described in step (b) above] was dissolved in a small amount of ethyl acetate, and 0.25 ml of a 4N solution of hydrogen chloride in dioxane was added to the solution. The mixture was then concentrated by distillation under reduced pressure. Pentane was added to the resulting concentrate, and the mixture was shaken and then the upper pentane layer was removed. The operation was repeated twice and the resulting oil was dried in vacuo, to give 0.235 g (yield 94%) of the title compound as a colorless oil.