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2-Methylcinnamic aldehyde → 1-(2-Benzyloxyphenyl)-3-methyl-4-phenylbutadiene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methylcinnamic aldehyde | HCID 7557 | — |
| 反応物 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 反応物 | 2-Benzyloxybenzyltriphenylphosphonium chloride | HCID 19423967 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 1-(2-Benzyloxyphenyl)-3-methyl-4-phenylbutadiene | HCID 54340925 | 90.2% |
反応手順
Following a procedure similar to that described in the first part of Preparation 3, 1.32 g of α-methylcinnamaldehyde, 4.47 g of 2-benzyloxybenzyltriphenylphosphonium chloride (prepared as described in Preparation 1) and 1.37 g of 1,8-diazabicyclo[5,4,0]-undec-7-ene were reacted in acetonitrile. The crude product thus obtained was purified as described in the first part of Preparation 3, to give 2.66 g (yield 90%) of 1-(2-benzyloxyphenyl)-3-methyl-4-phenylbutadiene as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05556864 |
| 出典データセット | uspto-grants-1996_09 |
| ORD ID | ord-bb1871ccbce247d3a54725dc09118cc0 |
| 出典メモ | uspto-grants-1996_09 |