1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-(2-Benzyloxyphenyl)-4-(2-chlorophenyl)butadiene

HRID 743403ノート

反応式

HRID 743403 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][CH:10]=O.[Cl-].[CH2:13]([O:20][C:21]1[CH:46]=[CH:45][CH:44]=[CH:43][C:22]=1[CH2:23][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.N12CCCN=C1CCCCC2>>[CH2:13]([O:20][C:21]1[CH:46]=[CH:45][CH:44]=[CH:43][C:22]=1[CH:23]=[CH:10][CH:9]=[CH:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

参加物

4

反応物 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 30140422-ChlorocinnamaldehydeHCID 194239672-Benzyloxybenzyltriphenylphosphonium chloride

生成物 1

HCID 538952741-(2-Benzyloxyphenyl)-4-(2-chlorophenyl)butadiene収率 90%

実験手順

Then, following a procedure similar to that described in the first part of Preparation 3, the whole of this 3-(2-chlorophenyl)-2-propenal was reacted with 7.97 g of 2-benzyloxybenzyltriphenylphosphonium chloride (prepared as described in Preparation 1) and 3.35 g of 1,8-diazabicyclo[5,4,0]undec-7-ene. The resulting crude product was purified as described in the first part of Preparation 3, to give 4.57 g (yield 90%) of 1-(2-benzyloxyphenyl)-4-(2-chlorophenyl)butadiene as an oil.

後処理

  1. customthat described in the first part of Preparation 3
  2. customThe resulting crude product was purified
  3. customas described in the first part of Preparation 3

出典と根拠

ORDレコード
ord-6a6118d3989b4dccaed45c721ceaf6b2
出典データセット
uspto-grants-1996_09
特許番号
US05556864

反応ノート

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