戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 74398作成日：2026年10月25日

Styrene Oxide → 2-(2-(3-(2-Hydroxy-2-phenylethoxy)phenoxy)ethyl)isoindoline-1,3-dione

https://huagongshe.com/reaction/74398

反応式

関与物質

役割名称HCID仕込み量
反応物Styrene OxideHCID 7276—
反応物2-[2-(3-Hydroxy-phenoxy)-ethyl]-isoindole-1,3-dioneHCID 58027534—
生成物2-(2-(3-(2-Hydroxy-2-phenylethoxy)phenoxy)ethyl)isoindoline-1,3-dioneHCID 67317562—

反応手順

Alkylation reaction of phenol 24 with styrene oxide gave 2-(2-(3-(2-hydroxy-2-phenylethoxy)phenoxy)ethyl)isoindoline-1,3-dione as yellow oil. Yield (0.85 g, 50%): 1H NMR (400 MHz, CDCl3) δ 7.99 (d, J=7.2 Hz, 1H), 7.41-7.53 (m, 3H), 7.28-7.38 (m, 5H), 7.12-7.16 (m, 1H), 6.60-6.65 (m, 1H), 6.52 (s, 1H), 6.48 (dd, J=8.0, 2.0 Hz, 1H), 4.79-4.82 (m, 1H), 4.19 (t, J=5.4 Hz, 2H), 3.72-3.84 (m, 4H).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08829244B2
出典データセットuspto-grants-2014_09
ORD IDord-5e398944ad2441beb58cd66c27aa4a09
出典メモuspto-grants-2014_09