HCID 15839226、化合物 → HCID 15839227、化合物
反応式
[C:1]1([C:7]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)(O)[CH:8]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]3[O:20][CH2:21][O:22][C:16]=3[CH:15]=2)[C:9]([O:11][CH3:12])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>Cl>[C:24]1([C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:8]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]3[O:20][CH2:21][O:22][C:16]=3[CH:15]=2)[C:9]([O:11][CH3:12])=[O:10])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1参加物
3
実験手順
Methyl (2RS)-3,3-diphenyl-3-hydroxy-2-(3,4-methylenedioxybenzyl)propanoate (0.309 g, 0.79 mmol) was dissolved in methanolic HCl (60 ml) (prepared by passing HCl gas through MeOH at 0° C.). After 4 days at ambient temperature the MeOH was removed by evaporation and replaced with fresh methanolic HCl. After a further 2 days the methanol was evaporated. The residue was recrystallized (MeOH) to give the title compound as a colorless solid (69 mg, 23%).
後処理
- customAfter 4 days at ambient temperature the MeOH was removed by evaporation
- customAfter a further 2 days the methanol was evaporated