関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 1,2-Diaminocyclohexane, trans- | HCID 43806 | — |
| 反応物 | 1-tert-Butyl-4-(3-chloro-2-methylpropyl)benzene | HCID 13251817 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | HCID 13251820 | HCID 13251820 | 83.5% |
反応手順
274 g of trans-1,2-diaminocyclohexane and 134.4 g of 3-(4-tert.-butylphenyl)-2-methylpropyl chloride (German Laid-Open Application DOS No. 2,752,096) were stirred for 10 hours at 140° C. and then cooled to +10° C. in an ice bath, and 200 ml of a 50% strength by weight sodium hydroxide solution were added slowly, followed by the addition of 200 ml of ether. The organic phase was separated off, dried over potassium hydroxide and distilled to give 151 g of N-(3-(4-tert.-butylphenyl)-2-methylpropyl)-trans-1,2-diaminocyclohexane of boiling point 175°-180° C./0.3 mbar. Yield: 83.3% of theory.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04599335 |
|---|
| 出典データセット | uspto-grants-1986_07 |
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| ORD ID | ord-9d6febe3472e4acb8c5384b0ade92637 |
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| 出典メモ | uspto-grants-1986_07 |
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