Hydrochloric Acid → Benzene, 1-chloro-4-(1,1-dimethylethyl)-

反応式

Cl.[C:2](Cl)([CH3:5])([CH3:4])[CH3:3].[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:2]([C:11]1[CH:12]=[CH:13][C:8]([Cl:7])=[CH:9][CH:10]=1)([CH3:5])([CH3:4])[CH3:3]

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 7964Chlorobenzene

HCID 10486tert-BUTYL CHLORIDE

生成物 1

HCID 77594Benzene, 1-chloro-4-(1,1-dimethylethyl)-収率 29.8%

反応条件

温度: 30 °C

実験手順

To 169 g of chlorobenzene was added 1.5 g of ferric chloride, and hydrogen chloride gas was blown into the mixture for 10 minutes. Then, 46 g of tert-butyl chloride was added dropwise to the mixture at 30° C. over a period of 1 hour. The mixture was maintained at 30° C. for 2 hours. The reaction mixture was washed with an aqueous solution of sodium carbonate and then with water, and evaporated under reduced pressure to give 25 g of 4-tert-butylchlorobenzene (pb.: 113° C./28mmHg).