Acetyl chloride → 3,3-Difluorooxolane-2,5-dione

HRID 745634ノート

反応式

HRID 745634 の反応式
C(OC(=O)C)(=O)C.C(Cl)(=O)C.[F:12][C:13]([F:21])([CH2:17][C:18]([OH:20])=[O:19])[C:14](O)=[O:15]>>[F:12][C:13]1([F:21])[CH2:17][C:18](=[O:20])[O:19][C:14]1=[O:15]

参加物

4

反応物 3

HCID 6367Acetyl chlorideHCID 7918Acetic AnhydrideHCID 695812,2-Difluorosuccinic acid

生成物 1

HCID 131892433,3-Difluorooxolane-2,5-dione

反応条件

温度
50 °C

実験手順

To a solution of 10.8 ml of acetic anhydride and 10.8 mL of acetyl chloride at 0° C. was added 10.80 g (0.070 mol) of 2,2-difluorosuccinic acid in several portions. The mixture was heated for 1 hr at 50° C. and cooled. The reaction was concentrated under reduced pressure to yield 2,2-difluorosuccinic anhydride.

後処理

  1. temperaturecooled
  2. concentrationThe reaction was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-3ac7df6006604464bb3f07a681d92e2c
出典データセット
uspto-grants-1986_07
特許番号
US04599330

反応ノート

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