1,10-Decanediamine → N-(10-aminodecyl)-aminomethanephosphonic acid monohydrate

HRID 745721ノート

反応式

HRID 745721 の反応式
Cl[CH2:2][P:3]([OH:6])(=[O:5])[OH:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH2:18]>O>[OH2:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][CH2:2][P:3]([OH:6])(=[O:5])[OH:4]

参加物

4

反応物 2

HCID 13171,10-DecanediamineHCID 75723P-(Chloromethyl)phosphonic acid

生成物 1

HCID 86740900N-(10-aminodecyl)-aminomethanephosphonic acid monohydrate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Chloromethanephosphonic acid (5.5 g, 42 mmoles) and 1.10-diaminodecane (44 g, 255 mmoles) were heated under reflux in water (200 cm3) for 20 hours. The water was removed and ethanol (400 cm3) added to the solid residue. The phosphonic acid was filtered off and dried. The crude yield was 11.4 g (87%). A sample was purified by recrystallization from water/ethanol to give N-(10-aminodecyl)-aminomethanephosphonic acid monohydrate as a fine white crystalline solid having a melting point of 238° C.

後処理

  1. customThe water was removed
  2. additionethanol (400 cm3) added to the solid residue
  3. filtrationThe phosphonic acid was filtered off
  4. customdried
  5. customA sample was purified by recrystallization from water/ethanol

出典と根拠

ORDレコード
ord-09381e4a41b946cbb8ee07e8ed0fa10d
出典データセット
uspto-grants-1986_07
特許番号
US04600429

反応ノート

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