HCID 23312424、化合物 → HCID 23312423、化合物

HRID 745757ノート

反応式

HRID 745757 の反応式
[ClH:1].C([NH:4][NH:5][C:6]1[S:7][C:8]2[CH2:14][CH2:13][CH2:12][CH2:11][C:9]=2[N:10]=1)=O>C(O)C.Cl>[ClH:1].[NH:5]([C:6]1[S:7][C:8]2[CH2:14][CH2:13][CH2:12][CH2:11][C:9]=2[N:10]=1)[NH2:4]

参加物

4

反応物 1

HCID 23312424HCID 23312424、化合物

生成物 1

HCID 23312423HCID 23312423、化合物収率 117.3%

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 702Ethanol溶媒

実験手順

A solution of 40.2 g of 1-formyl-2-(4,5,6,7-tetrahydro-benzothiazolyl)-hydrazine hydrochloride in 400 ml of ethanol and 100 ml of concentrated hydrochloric acid is boiled under reflux for 4 hours. Concentration of the mixture and drying of the residue gives 41.5 g of 2-hydrazino-4,5,6,7-tetrahydro-benzothiazole hydrochloride of melting point 177°-179° C. as a hygroscopic substance of sufficient purity for further reactions.

後処理

  1. temperatureunder reflux for 4 hours
  2. customConcentration of the mixture and drying of the residue

出典と根拠

ORDレコード
ord-64f5eeb8f2124744bac4eef26b3bfdbc
出典データセット
uspto-grants-1986_07
特許番号
US04600722

反応ノート

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