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llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
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Hydroxylamine, O-(3-chloro-2-propenyl)-, hydrochloride → 2-(3-Chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

HRID 746124
ノート
印刷プレビュー

反応式

HRID 746124 の反応式
[C:1]([CH:6]1[C:11](=[O:12])[CH2:10][CH:9]([CH:13]2[CH:18]([CH3:19])[CH:17]([CH2:20][CH3:21])[CH2:16][CH:15]([O:22][CH2:23][CH:24]([CH3:26])[CH3:25])[O:14]2)[CH2:8][C:7]1=[O:27])(=O)[CH2:2][CH2:3][CH3:4].Cl.[Cl:29][CH:30]=[CH:31][CH2:32][O:33][NH2:34]>C(O)C.C([O-])(=O)C.[Na+]>[Cl:29][CH:30]=[CH:31][CH2:32][O:33][NH:34][CH2:4][CH2:3][CH2:2][CH:1]=[C:6]1[C:7](=[O:27])[CH2:8][CH:9]([CH:13]2[CH:18]([CH3:19])[CH:17]([CH2:20][CH3:21])[CH2:16][CH:15]([O:22][CH2:23][CH:24]([CH3:26])[CH3:25])[O:14]2)[CH2:10][C:11]1=[O:12]
参加物実験手順後処理出典と根拠反応ノート

参加物

5

反応物 2

HCID 158057Hydroxylamine, O-(3-chloro-2-propenyl)-, hydrochlorideHCID 134214452-Butyryl-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

生成物 1

HCID 543533332-(3-Chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 517045
Sodium Acetate
溶媒

実験手順

10.2 parts by weight of 2-butyryl-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione were dissolved in 100 parts by volume of ethanol, and 2.42 parts by weight of sodium acetate and 3.86 parts by weight of O-(3-chloroallyl)-hydroxylamine hydrochloride were added. The mixture was stirred for several hours at room temperature and then poured into ice-water, and the resulting mixture was extracted with methylene chloride. The methylene chloride phase was evaporated off, leaving 11.1 parts by weight of 2-(3-chloroallyloxyaminobutylidene)-5-(3-methyl-4-ethyl-6-isobutoxytetrahydropyran-2-yl)-cyclohexane-1,3-dione as a yellow oil of refractive index nD22 1.5129.

後処理

  1. additionwere added
  2. extractionthe resulting mixture was extracted with methylene chloride
  3. customThe methylene chloride phase was evaporated off

出典と根拠

ORDレコード
ord-2679ef3b0ea54d12a1196452c5a1ec3e
出典データセット
uspto-grants-1986_07
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US04602935

反応ノート

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