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Water → 1-Amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | N-Boc-1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane | HCID 70445455 | — |
| 溶媒 | Trifluoroacetic acid | HCID 6422 | — |
| 生成物 | 1-Amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane | HCID 20164442 | — |
反応手順
N-Boc-1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane is dissolved in trifluoroacetic acid and the solution is stirred overnight. Water is added and the mixture is made basic with 20% KOH. The mixture is extracted with ether, and the organic layer is dried over Na2SO4 and is evaporated to yield 1-amino-1-(2,2,5,5-tetramethyl-1-cyclopentyl)ethenylcyclopropane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04603012 |
| 出典データセット | uspto-grants-1986_07 |
| ORD ID | ord-fa1ab37073b8466690f34c54835671c3 |
| 出典メモ | uspto-grants-1986_07 |