Potassium Iodide → HCID 69299641、化合物
反応式
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH:5]=[CH:6][C:7]=1[C:8]#[N:9].Br[CH2:18][CH2:19][O:20][CH3:21].[I-].[K+].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:18][CH2:19][O:20][CH3:21])=[CH:12][CH:11]=2)[CH:5]=[CH:6][C:7]=1[C:8]#[N:9]参加物
6
実験手順
A mixture of 3-fluoro-4′-hydroxy-1,1′-biphenyl-4-carbonitrile (0.50 g, 2.35×10−3 mol), 1-bromo-2-methoxyethane (0.33 g, 2.35×10−3 mol), potassium iodide (0.04 g, 2.35×10−4 mol) and potassium carbonate (1.30 g, 9.40×10−3 mol) in butanone (20 cm3) was reacted, worked up and purified as described for compound 3 in Example 2. Yield 0.40 g (63%), GC purity (99.86%).
後処理
- customwas reacted
- custompurified
出典と根拠
- ORDレコード
- ord-e40f0fd3fe574bbbbf7bf2ba072ebddc
- 出典データセット
- uspto-grants-2008_07
- 特許番号
- US07396487B2
反応ノート
読み込み中…