2-Acetylfuran → HCID 535936、化合物

反応式

[C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)(=[O:3])[CH3:2].CO[CH:11](OC)[N:12]([CH3:14])[CH3:13]>>[CH3:11][N:12]([CH3:14])[CH:13]=[CH:2][C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)=[O:3]

参加物

反応物 2

HCID 145052-Acetylfuran

HCID 78373Dimethylformamide dimethyl acetal

生成物 1

HCID 535936HCID 535936、化合物収率 97%

反応条件

温度: 100 °C

実験手順

A mixture of 2-acetylfuran (25.0 g, 0.227 mol) and N,N-dimethylformamide dimethylacetal (40 ml) was stirred at 100° C. for 9 hours. After cooling as it was, the reaction mixture was concentrated. To the residue were added diethyl ether and hexane. The resulting solid was collected by filtration and washed with hexane, to give the title compound (36.5 g, 97%) as a brown solid.

後処理

temperatureAfter cooling as it
concentrationthe reaction mixture was concentrated
additionTo the residue were added diethyl ether and hexane
filtrationThe resulting solid was collected by filtration
washwashed with hexane

出典と根拠

ORDレコード: ord-f719234000f54031b9cac03a1799a13f
出典データセット: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07396836B2

反応ノート

読み込み中…

参加物