Hydrochloric Acid → N-[3-(3-Aminopropyl)-4-[(benzyloxy)methyl]thiazol-2(3H)-ylidene]-5-methoxy-2-pyridinamine
反応式
[OH:1][CH2:2][C:3]1[N:4]([CH2:17][CH2:18][CH2:19][NH:20]C(=O)OC(C)(C)C)[C:5](=[N:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][N:10]=2)[S:6][CH:7]=1.NCCCN1C(CO[CH2:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)=CSC1=NC1C=CC(OC(F)(F)F)=CC=1.Cl>>[NH2:20][CH2:19][CH2:18][CH2:17][N:4]1[C:3]([CH2:2][O:1][CH2:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)=[CH:7][S:6][C:5]1=[N:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][N:10]=1参加物
4
反応物 3
生成物 1
実験手順
The compound (283 mg) obtained in the above (1) was treated in a similar manner to in Example 208 (3), (4) to give the title compound (128 mg) as hydrochloride.