Ethyl 2-benzyl-8-hydroxy-1-oxo-3,4-dihydropyrrolo[1,2-a]pyrazine-7-carboxylate → 2-[(4-Fluorophenyl)methyl]-8-hydroxy-1-oxo-3,4-dihydropyrrolo[1,2-a]pyrazine-7-carboxylic acid
反応式
C(N1CCN2C=C(C(OCC)=O)C(O)=C2C1=O)C1C=CC=CC=1.[F:24][C:25]1[CH:47]=[CH:46][C:28]([CH2:29][N:30]2[CH2:35][CH2:34][N:33]3[CH:36]=[C:37]([C:40]([O:42]CC)=[O:41])[C:38]([OH:39])=[C:32]3[C:31]2=[O:45])=[CH:27][CH:26]=1>>[F:24][C:25]1[CH:26]=[CH:27][C:28]([CH2:29][N:30]2[CH2:35][CH2:34][N:33]3[CH:36]=[C:37]([C:40]([OH:42])=[O:41])[C:38]([OH:39])=[C:32]3[C:31]2=[O:45])=[CH:46][CH:47]=1参加物
3
反応物 2
生成物 1
実験手順
The title compound was prepared using a procedure similar to that described in Example 2, except that ethyl 2-benzyl-8-hydroxy-1-oxo-1,2,3,4-tetrahydropyrrolo-[1,2-α]pyrazine-7-carboxylate was substituted wit ethyl 2-(4-fluorobenzyl)-8-hydroxy-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-α]pyrazine-7-carboxylate.
出典と根拠
- ORDレコード
- ord-1b92f05d3a6842a891db6632a0c9741c
- 出典データセット
- uspto-grants-2008_07
- 特許番号
- US07399763B2
反応ノート
読み込み中…