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Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-{3-[2-(3-Trifluoromethylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate | HCID 21980299 | — |
| 反応物 | 2-(3-Trifluoromethylphenyl)4-iodomethyl-5-methyloxazole | HCID 22493681 | — |
| 生成物 | 2-{3-[2-(3-Trifluoromethylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic Acid | HCID 22493685 | — |
反応手順
Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-trifluoromethylphenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 54 of molecular weight 503.52 (C27H28F3NO5), MS(ESI): 504.37 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07399777B2 |
| 出典データセット | uspto-grants-2008_07 |
| ORD ID | ord-41e25d09d6494ee2818877837820f7bf |
| 出典メモ | uspto-grants-2008_07 |