関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 4-Benzyloxy-1-methyl-1H-indole-2-carboxylic acid | HCID 4777678 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 4-Benzyloxy-1-methyl-1H-indole-2-carbonyl chloride | HCID 22054872 | — |
反応手順
To a stirred suspension of 4-benzyloxy-1-methyl-1H-indole-2-carboxylic acid (0.75 g) in benzene (5 mL) was added thionyl chloride (2.8 mL) in benzene (5 mL) followed by heated at 80° C. for 45 min. to give a clear orange solution. Evaporation to dryness gave 0.80 g of the title compound as an orange solid, which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07402604B2 |
|---|
| 出典データセット | uspto-grants-2008_07 |
|---|
| ORD ID | ord-9b7c208217634ef2acf1a25b4db3a35f |
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| 出典メモ | uspto-grants-2008_07 |
|---|
