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Cesium carbonate → 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cesium carbonate | HCID 10796 | — |
| 反応物 | 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate | HCID 2776019 | — |
| 反応物 | (4-(Trifluoromethoxy)benzyl)malononitrile | HCID 22235052 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile | HCID 22235048 | 29% |
反応手順
Using 0.3 g of (4-(trifluoromethoxy)benzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.073 g of cesium carbonate, and 0.35 g of 2,2,3,3,3-pentafluoropropyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 0.12 g of 2-(2,2,3,3,3-pentafluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile (the present compound (5)).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07402691B2 |
| 出典データセット | uspto-grants-2008_07 |
| ORD ID | ord-062feb08cf88480ab7deb784467f5087 |
| 出典メモ | uspto-grants-2008_07 |