6-Bromo-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid → HCID 69157753、化合物
反応式
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[N:7]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH3:23])(=[O:22])=[O:21])=[CH:16][CH:15]=1)[C:6]([C:24]([OH:26])=[O:25])=[C:5]2[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1.[CH3:33][O:34][C:35]([C:37]1[CH:42]=[C:41]([CH2:43]O)[CH:40]=[CH:39][N:38]=1)=[O:36]>>[CH3:33][O:34][C:35]([C:37]1[CH:42]=[C:41]([CH2:43][O:25][C:24]([C:6]2[N:7]([CH2:13][C:14]3[CH:15]=[CH:16][C:17]([S:20]([CH3:23])(=[O:21])=[O:22])=[CH:18][CH:19]=3)[C:8](=[O:12])[C:9]3[C:4]([C:5]=2[C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)=[CH:3][C:2]([Br:1])=[CH:11][CH:10]=3)=[O:26])[CH:40]=[CH:39][N:38]=1)=[O:36]参加物
3
実験手順
The present compound was synthesized by a method similar to that in Example 200 and using 6-bromo-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (330 mg) and 4-hydroxymethylpyridin-2-carboxylic acid methyl ester. A colorless powder (410 mg).
後処理
- customThe present compound was synthesized by a method similar to that in Example 200