化工社化工社 化学情報印刷レポート · 研究参考用
Mafenide Hydrochloride → 6-bromo-1-oxo-4-phenyl-2-(4-sulfamoylbenzyl)-1,2-dihydroisoquinoline-3-carboxylic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Mafenide Hydrochloride | HCID 67313 | — |
| 反応物 | 6-Bromo-4-phenyl-3-isocoumarincarboxylic acid | HCID 23060777 | — |
| 生成物 | 6-bromo-1-oxo-4-phenyl-2-(4-sulfamoylbenzyl)-1,2-dihydroisoquinoline-3-carboxylic Acid | HCID 23060824 | 71% |
反応手順
The title compound (3.64 g, 71%) was synthesized by a method similar to that in Example 331 and using 6-bromo-1-oxo-4-phenyl-1H-isochromen-3-carboxylic acid and 4-sulfamoylbenzylamine hydrochloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07402595B2 |
| 出典データセット | uspto-grants-2008_07 |
| ORD ID | ord-f36f6eac03fa414c899a8047cfb26c6f |
| 出典メモ | uspto-grants-2008_07 |