N-[2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-phenyl]-methanesulphonamide → HCID 11463229、化合物

反応式

C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:21])[CH:16](OCC)O)=[CH:11][C:10]=1[NH:22][S:23]([CH3:26])(=[O:25])=[O:24])C1C=CC=CC=1.[CH3:27][C:28]([NH2:37])([CH3:36])[CH2:29][CH2:30][N:31]1[CH:35]=[N:34][CH:33]=[N:32]1>>[CH3:36][C:28]([NH:37][CH2:16][CH:15]([C:12]1[CH:13]=[CH:14][C:9]([OH:8])=[C:10]([NH:22][S:23]([CH3:26])(=[O:24])=[O:25])[CH:11]=1)[OH:21])([CH3:27])[CH2:29][CH2:30][N:31]1[CH:35]=[N:34][CH:33]=[N:32]1

参加物

反応物 2

HCID 10317570N-[2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-phenyl]-methanesulphonamide

HCID 597541992-methyl-4-(1H-1,2,4-triazol-1-yl)butan-2-amine

生成物 1

HCID 11463229HCID 11463229、化合物

実験手順

The target compound is prepared analogously to the methods described for Example 7 from 379 mg (1 mmol) N-[2-benzyloxy-5-[2-ethoxy-2-hydroxy-acetyl)-phenyl]-methanesulphonamide and 154 mg (1 mmol) 1,1-dimethyl-3-[1,2,4]triazol-1-yl-propylamine. Colourless solid.

後処理

customThe target compound is prepared analogously to the methods

出典と根拠

ORDレコード: ord-c0c8927d406945cdb871dbe82f337229
出典データセット: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07405232B2

反応ノート

読み込み中…