Acetic Anhydride → N-(3-fluoro-2-methylphenyl)acetamide
反応式
[F:1][C:2]1[C:3]([CH3:9])=[C:4]([CH:6]=[CH:7][CH:8]=1)[NH2:5].[C:10](OC(=O)C)(=[O:12])[CH3:11]>CCO>[F:1][C:2]1[C:3]([CH3:9])=[C:4]([NH:5][C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][CH:8]=1参加物
4
実験手順
To a solution of 3-fluoro-2-methylaniline (2.65 g, 21.2 mmol) in EtOH (25 mL) at 0° C. was added acetic anhydride (2.60 g, 25.5 mmol). The mixture was stirred at rt overnight then concentrated under reduced pressure to give the title compound (3.54 g). LCMS: m/z 168 [M+H]+
後処理
- concentrationthen concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-bf14e746a1634611961a1369b5826538
- 出典データセット
- uspto-grants-2008_07
- 特許番号
- US07405234B2
反応ノート
読み込み中…