Allylamine → Allyl-(2,2-dimethyl-pent-4-enylidene)-amine

HRID 751461ノート

反応式

HRID 751461 の反応式
[CH3:1][C:2]([CH3:8])([CH2:5][CH:6]=[CH2:7])[CH:3]=O.[CH2:9]([NH2:12])[CH:10]=[CH2:11]>C1C=CC=CC=1>[CH2:9]([N:12]=[CH:3][C:2]([CH3:1])([CH3:8])[CH2:5][CH:6]=[CH2:7])[CH:10]=[CH2:11]

参加物

4

反応物 2

HCID 7853AllylamineHCID 796362,2-Dimethylpent-4-enal

生成物 1

HCID 22928390Allyl-(2,2-dimethyl-pent-4-enylidene)-amine収率 100%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

2,2-Dimethyl-4-pentenal (2.8 g, 25 mmol) was dissolved in 15 mL benzene. To this solution allylamine (2.85 g, 50 mmol) was added. A few molecular sieves were used to absorb water generated during the reaction. The mixture was stirred at room temperature overnight. Removal of the solvent and excess amount of allylamine on rotavapor provided 3.76 g of the title compound as clear liquid (yield 100%). 1H-NMR (400 MHz, CDCl3): •7.52(s, 1H), 5.99-5.90(m, 1H), 5.80-5.70(m, 1H), 5.15-4.99(m, 4H), 4.01-3.99(m, 2H), 2.17(d, 2H), 1.06(s, 6H).

後処理

  1. customto absorb water
  2. customgenerated during the reaction
  3. customRemoval of the solvent and excess amount of allylamine on rotavapor

出典と根拠

ORDレコード
ord-f24895c55c78484da8f31d9a87f89b0d
出典データセット
uspto-grants-2008_07
特許番号
US07405209B2

反応ノート

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