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Benzaldehyde → HCID 178418783、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzaldehyde | HCID 240 | — |
| 反応物 | 2-Aminopyridine | HCID 10439 | — |
| 反応物 | Tert-Butyl isocyanide | HCID 23577 | — |
| 反応物 | Cyclohexanecarbonyl chloride | HCID 75938 | — |
| 溶媒 | Perchloric Acid | HCID 24247 | — |
| 生成物 | HCID 178418783 | HCID 178418783 | — |
反応手順
Example 10 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process steps b) to d) by reacting the resultant reaction product with 0.4 mmol cyclohexylcarboxylic acid chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07087607B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-cb1d1f9e1bc94670a80cb99ed22a0e19 |
| 出典メモ | uspto-grants-2006_08 |