Tricyclo(3.3.1.13,7)dec-1-ylmethylamine → (+/-)-1-(1-Adamantylmethyl)-4-(hydroxymethyl)-4-isobutylimidazolidin-2-one
反応式
C(O[C:6]([NH:8][C:9]([CH2:17]O)([CH2:13][CH:14]([CH3:16])[CH3:15])[C:10]([OH:12])=O)=[O:7])(C)(C)C.[NH2:19][CH2:20][C:21]12[CH2:30][CH:25]3[CH2:26][CH:27]([CH2:29][CH:23]([CH2:24]3)[CH2:22]1)[CH2:28]2>>[C:21]12([CH2:20][N:19]3[CH2:17][C:9]([CH2:10][OH:12])([CH2:13][CH:14]([CH3:15])[CH3:16])[NH:8][C:6]3=[O:7])[CH2:28][CH:27]3[CH2:26][CH:25]([CH2:24][CH:23]([CH2:29]3)[CH2:22]1)[CH2:30]2参加物
3
実験手順
The title compound was prepared following procedures analogous to those described in Example 27 using (±)-2-(tert-butoxycarbonylamino)-2-(hydroxymethyl)-4-methylpentanoic acid and 1-(aminomethyl)adamantane. MS m/z=321.
出典と根拠
- ORDレコード
- ord-be24594330af48f5870c8035a084a492
- 出典データセット
- uspto-grants-2014_09