2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

HRID 751963

反応式

Cc1cccc(N)c1C.Cc1cc(C(=O)O)cc(Cl)n1.C1CCN(C1)C(=[N+]2CCCC2)F.F[P-](F)(F)(F)(F)F.CN1CCOCC1.CN(C)C=O>>Cc1cc(C(=O)Nc2cccc(C)c2C)cc(Cl)n1

addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
addition380 uL MeCN solvent were added to the transfer plate
aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
addition180 uL MeCN added to filter plate 1 for LCMS analysis
aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM