HCID 67353219、化合物 → Methyl 2-(3-(4-(3-(2,4-difluorophenyl)ureido)-3-methylphenyl) isoxazole-5-carboxamido)-3-methylbutanoate
反応式
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:27])[NH:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:22]=[C:21]([C:23]([OH:25])=O)[O:20][N:19]=2)=[CH:14][C:13]=1[CH3:26].FC1C=CC=C(F)C=1NC(=O)NC1C=CC(C2C=C(C([NH:52][CH:53]([CH:58]([CH3:60])[CH3:59])[C:54]([O:56][CH3:57])=[O:55])=O)ON=2)=CC=1C>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10](=[O:27])[NH:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:22]=[C:21]([C:23]([NH:52][CH:53]([CH:58]([CH3:60])[CH3:59])[C:54]([O:56][CH3:57])=[O:55])=[O:25])[O:20][N:19]=2)=[CH:14][C:13]=1[CH3:26]参加物
3
実験手順
The title compound was prepared from 3-(4-(3-(2,4-difluorophenyl)ureido)-3-methylphenyl)isoxazole-5-carboxylic acid using the same procedure as described for preparation of the compound of step 8 of Example 98. The title compound was obtained in crude form.
出典と根拠
- ORDレコード
- ord-d1889ed71c8d41579a9a0a4a0a109f47
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08835428B2
反応ノート
読み込み中…