化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Benzoic acid, 5-chloro-2-hydroxy-, methyl ester | HCID 77684 | — |
| 反応物 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate | HCID 80366 | — |
| 生成物 | 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid | HCID 43141863 | — |
反応手順
Commercially available, methyl 5-chloro-2-hydroxybenzoate (Maybridge), potassium carbonate, 2,2,2-trifluoroethyl trifluoromethanesulfonate (TCI) and sodium hydroxide were processed according to the method of Example 130A to obtain the title compound. MS (ESI+) m/z 253 (M−H)'.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08835475B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-092e969b2e014dc0aba635b79043f1a2 |
| 出典メモ | uspto-grants-2014_09 |