2-Aminobiphenyl → N2,N4-bis(2-phenylphenyl)-5-methyl-2,4-pyrimidinediamine

HRID 76481

反応式

HRID 76481 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.Cl[C:15]1[N:20]=[C:19](Cl)[C:18]([CH3:22])=[CH:17][N:16]=1>>[C:8]1([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH:1][C:15]2[N:20]=[C:19]([NH:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:18]([CH3:22])=[CH:17][N:16]=2)[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

参加物

3

反応物 2

HCID 70152-AminobiphenylHCID 74508Pyrimidine, 2,4-dichloro-5-methyl-

生成物 1

HCID 22060710N2,N4-bis(2-phenylphenyl)-5-methyl-2,4-pyrimidinediamine

実験手順

In like manner to the preparation of 5-fluoro-N2,N4-bis(3-hydroxyphenyl)-2,4-pyrimidinediamine, 2-aminobiphenyl and 2,4-dichloro-5-methylpyrimidine were reacted to provide N2,N4-bis(2-phenylphenyl)-5-methyl-2,4-pyrimidinediamine. LCMS: ret. time: 30.47 min.; purity: 91%; MS (m/e): 429 (MH|).

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-8335221da65e47e0b28496bd5c47c355
出典データセット
uspto-grants-2014_09
特許番号
US08835430B2

関連ノート

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