化工社化工社 化学情報印刷レポート · 研究参考用
3-Aminophenol → N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Aminophenol | HCID 11568 | — |
| 反応物 | Pyrimidine, 2,4-dichloro-5-methyl- | HCID 74508 | — |
| 反応物 | R-112 | HCID 9904854 | — |
| 生成物 | N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine | HCID 22061056 | — |
反応手順
In a manner analogous to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,4-dichloro-5-methylpyrimidine with 3-hydroxyaniline gave N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine. LCMS: ret. time: 16.76 min.; purity: 100%, MS (m/e): 309 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08835430B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-8c6534cf8c2b4b498f754b21096ee7d9 |
| 出典メモ | uspto-grants-2014_09 |