3,5-Dimethoxyphenol → 5-(4,6-Dihydroxy-1-benzofuran-2-yl)benzene-1,2,3-triol

HRID 76830

反応式

HRID 76830 の反応式
C[O:2][C:3]1[CH:4]=[C:5](O)[CH:6]=[C:7]([O:9]C)[CH:8]=1.Br[CH2:13][C:14]([C:16]1[CH:21]=[C:20]([O:22]C)[C:19]([O:24]C)=[C:18]([O:26]C)[CH:17]=1)=[O:15]>>[OH:2][C:3]1[C:4]2[CH:13]=[C:14]([C:16]3[CH:17]=[C:18]([OH:26])[C:19]([OH:24])=[C:20]([OH:22])[CH:21]=3)[O:15][C:5]=2[CH:6]=[C:7]([OH:9])[CH:8]=1

参加物

3

反応物 2

HCID 103833,5-DimethoxyphenolHCID 36857322-Bromo-1-(3,4,5-trimethoxyphenyl)ethanone

生成物 1

HCID 867627435-(4,6-Dihydroxy-1-benzofuran-2-yl)benzene-1,2,3-triol収率 62%

実験手順

This compound was prepared using Method A from 3,5-dimethoxyphenol and 2-bromo-1-(3,4,5-trimethoxyphenyl)ethanone: Yield 62% following procedures A.2 and A.5; m.p. 260° C. (dec.); IR 3442, 3326, 1600, 1539, 1470, 1313, 1197, 1072, 1037 cm−1; 1H NMR (500 MHz, δ ppm, DMSO-d6) 9.67 (s, 1H), 9.22 (s, 1H), 8.97 (s, 2H), 8.29 (s, 1H), 6.81 (s, 1H), 6.69 (s, 2H), 6.37 (s, 1H), 6.14 (s, 1H); 13C NMR (75 MHz, δ ppm, CD3OD) 158.3, 157.3, 155.0, 151.9, 147.4, 134.8, 123.8, 113.1, 104.8, 98.7, 97.7, 90.8.

後処理

  1. customThis compound was prepared

出典と根拠

ORDレコード
ord-39a498a1309b43baafe8a360c1cd72e2
出典データセット
uspto-grants-2014_09
特許番号
US08835659B2

関連ノート

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