化工社化工社 化学情報印刷レポート · 研究参考用
Diisopropyl Ether → D-tert-leucine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diisopropyl Ether | HCID 7914 | — |
| 反応物 | L-tert-Leucine | HCID 164608 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | D-tert-leucine | HCID 6950340 | 90% |
反応手順
The filtrate obtained at dibenzoyl-d-tartrate salt stage (step.ii), was treated with a small amount of diisopropyl ether to remove any traces of dibenzoyl-d-tartaric acid and was concentrated under reduced pressure at 55° C. The residue obtained was stirred with small amount of acetone and filtered to obtain D-tert-leucine as a colorless solid (90% yield, 98.8% D-tert-leucine and 1.2% L-tert-leucine).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08835676B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-2717b3f8bfa84c05a7accb02e8c22307 |
| 出典メモ | uspto-grants-2014_09 |