Decanal → Decanal Octreotide

関与物質

反応手順

50 mg of octreotide was dissolved in 2 mL of 20 mM sodium cyanoborohydride (Mw 62.84, NaCNBH3) (2.51 mg) solution in 0.1 M acetate buffer at pH 5. 13.7 mg of Decanal (Mw 156.27) (OCT:DCL=1:2) was added by direct injection to the peptide solution. The reaction was allowed to proceed overnight at 4° C. The mixture was separated by centrifugation. The precipitated PAL-OCT was freeze-dried.

情報源と証拠