化工社化工社 化学情報印刷レポート · 研究参考用
4-Amino-2-chlorophenol → 4-(2-(N-methylcarbamoyl)4-pyridyloxy)-3-chloroaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Amino-2-chlorophenol | HCID 77578 | — |
| 反応物 | 4-Chloro-N-methylpicolinamide | HCID 1476814 | — |
| 生成物 | 4-(2-(N-methylcarbamoyl)4-pyridyloxy)-3-chloroaniline | HCID 23614562 | — |
反応手順
Entry 20: According to Method A2, Step 4, 4-amino-2-chlorophenol was reacted with 4-chloro-N-methyl-2-pyridinecarboxamide, which had been synthesized according to Method A2, Step 3b, to give 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)-3-chloroaniline. 5-(Trifluoromethyl)-2-methoxyaniline was converted into 5-(trifluoromethyl)-2-methoxyphenyl isocyanate according to Method B1. 5-(Trifluoromethyl)-2-methoxyphenyl isocyanate was reacted with 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)-3-chloroaniline according to Method C1a to afford the urea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08841330B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-70e9c8742f5b40bfa5aaf38e1348c3b9 |
| 出典メモ | uspto-grants-2014_09 |