戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 78357作成日：2026年10月26日

2-Methoxy-5-(trifluoromethyl)aniline → 3-(4-Aminophenoxy)benzoic acid

https://huagongshe.com/reaction/78357

反応式

関与物質

役割名称HCID仕込み量
反応物2-Methoxy-5-(trifluoromethyl)anilineHCID 600637—
反応物Benzene, 2-isocyanato-1-methoxy-4-(trifluoromethyl)-HCID 11983909—
反応物3-(4-Aminophenoxy)benzoic acidHCID 23009036—
生成物3-(4-Aminophenoxy)benzoic acidHCID 23009036—
生成物N-(5-(trifluoromethyl)-2-methoxyphenyl)-N'-(3-carboxyphenyl)ureaHCID 23614600—

反応手順

Entry 38: 4-(3-Carboxyphenoxy)aniline was synthesized according to Method A11. 5-(Trifluoromethyl)-2-methoxyaniline was converted into 5-(trifluoromethyl)-2-methoxyphenyl isocyanate according to Method B1. 4-(3-Carboxyphenoxy)aniline was reacted with 5-(trifluoromethyl)-2-methoxyphenyl isocyanate according to Method C1f to afford N-(5-(trifluoromethyl)-2-methoxyphenyl)-N′-(3-carboxyphenyl)urea, which was coupled with 5-amino-2-methoxypyridine according to Method D1c.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08841330B2
出典データセットuspto-grants-2014_09
ORD IDord-67f2b2ac84e94ffb8d5869c27c66424c
出典メモuspto-grants-2014_09