化工社化工社 化学情報印刷レポート · 研究参考用
HRID 78406作成日：2026年10月26日
Benzene, (2-bromoethoxy)- → 4,5-Dimethyl-3-(2-phenoxy-ethyl)-3H-thiazol-2-ylideneamine hydrobromide
https://huagongshe.com/reaction/78406
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzene, (2-bromoethoxy)- | HCID 68526 | — |
| 反応物 | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| 生成物 | 4,5-Dimethyl-3-(2-phenoxy-ethyl)-3H-thiazol-2-ylideneamine hydrobromide | HCID 68621208 | 50.6% |
反応手順
A mixture of 4,5-dimethylthiazol-2-ylamine (1.0 g, 7.8 mmol) and (2-bromo-ethoxy)benzene (1.9 g, 9.4 mmol) were heated neat to 85° C. for 19 hours. The mixture was cooled to ambient temperature and the residue was crystallized from isopropanol. The solid was collected by filtration and dried under vacuum to afford 1.3 g (50%) of the title compound. MS (DCI/NH3) m/z 249 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08841334B2 |
|---|
| 出典データセット | uspto-grants-2014_09 |
|---|
| ORD ID | ord-83cb530fe84542689d937de7db6523a9 |
|---|
| 出典メモ | uspto-grants-2014_09 |
|---|
