2-Bromoethyl methyl ether → 3a-Ethoxy-3-(2-methoxy-ethyl)-tetrahydro-furo[3,4-d]thiazol-2-ylideneamine

反応式

[CH2:1]([O:3][C:4]12[CH2:11][O:10][CH2:9][CH:8]1[S:7][C:6]([NH2:12])=[N:5]2)[CH3:2].Br[CH2:14][CH2:15][O:16][CH3:17]>>[CH2:1]([O:3][C:4]12[CH2:11][O:10][CH2:9][CH:8]1[S:7][C:6](=[NH:12])[N:5]2[CH2:14][CH2:15][O:16][CH3:17])[CH3:2]

参加物

反応物 2

HCID 809722-Bromoethyl methyl ether

HCID 670954813a-Ethoxy-3a,4,6,6a-tetrahydrofuro[3,4-d]thiazol-2-ylamine

生成物 1

HCID 866408563a-Ethoxy-3-(2-methoxy-ethyl)-tetrahydro-furo[3,4-d]thiazol-2-ylideneamine

実験手順

The product from Example 125B and 1-bromo-2-methoxyethane were processed using the method described in Example 12A to afford the title compound. MS (ESI+) m/z 247 (M+H)+.

出典と根拠

ORDレコード: ord-76178a46bb654fc58625aad4ac09567a
出典データセット: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08841334B2

反応ノート

読み込み中…