化工社化工社 化学情報印刷レポート · 研究参考用
4-Quinolinecarboxylic acid → 4-Quinolinecarbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Quinolinecarboxylic acid | HCID 10243 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | 4-Quinolinecarbonyl chloride | HCID 9990126 | — |
反応手順
A solution of 4-quinolinecarboxylic acid (Aldrich, 0.25 g, 1.4 mmol) in 5 mL of thionyl chloride was warmed to reflux and allowed to stir for 1 hour. The mixture was then cooled to ambient temperature and concentrated under reduced pressure. This material was dissolved in 10 mL toluene and concentrated under reduced pressure (3×) to afford the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08841334B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-cdafd995a22746e6b7c3dd5a072b0f2f |
| 出典メモ | uspto-grants-2014_09 |