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HRID 78459作成日:2026年10月25日

Furan, 2-(bromomethyl)tetrahydro- → 4,5-Dimethyl-3-(tetrahydrofuran-2-ylmethyl)-1,3-thiazol-2(3H)-ylideneamine hydrobromide

https://huagongshe.com/reaction/78459

反応式

関与物質

役割名称HCID仕込み量
反応物Furan, 2-(bromomethyl)tetrahydro-HCID 14501—
反応物2-Amino-4,5-dimethyl-1,3-thiazoleHCID 73238—
生成物4,5-Dimethyl-3-(tetrahydrofuran-2-ylmethyl)-1,3-thiazol-2(3H)-ylideneamine hydrobromideHCID 68621760—

反応手順

A mixture of 2-amino-4,5-dimethylthiazole and 2-(bromomethyl)tetrahydrofuran were processed using the method described in Example 12A to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.43-1.64 (m, 1H) 1.73-2.00 (m, 3H) 2.17 (s, 3H) 2.19 (s, 3H) 3.53-3.68 (m, 1H) 3.71-3.85 (m, 1H) 3.91-4.17 (m, 3H) 9.34 (s, 1H),), MS (DCI/NH3) m/z 212 (M+H)+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08841334B2
出典データセットuspto-grants-2014_09
ORD IDord-fe8c0ca38329459780cca436ad88484e
出典メモuspto-grants-2014_09