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Methanol → HCID 59471788、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 3-Amino-6-(pyridin-3-yl)pyrazine-2-carboxylic acid | HCID 59472154 | — |
| 生成物 | HCID 59471788 | HCID 59471788 | 97% |
反応手順
To 3-amino-6-(3-pyridyl)pyrazine-2-carboxylic acid (2 g, 9.251 mmol) in MeOH (50 mL) was added conc. H2SO4 (907.3 mg, 493.1 μL, 9.251 mmol) and the mixture heated to reflux for 2 hours. The solvent was removed in vacuo and the mixture neutralised with aq. Na2CO3. The resulting brown solid was collected by filtration and dried (2.08 g, 97% Yield). MS (ES+) 231
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08841308B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-8282d7038caf4e1194a7dd66edba6051 |
| 出典メモ | uspto-grants-2014_09 |