Phosgen toluene → 2-(14-(4-Isocyanatophenoxy)-3,6,9,12-tetraoxatetradecyloxy)tetrahydro-2H-pyran

HRID 78711

反応式

HRID 78711 の反応式
[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18][O:19][CH2:20][CH2:21][O:22][C:23]1[CH:29]=[CH:28][C:26]([NH2:27])=[CH:25][CH:24]=1.[C:30](Cl)(Cl)=[O:31].C1(C)C=CC=CC=1>>[N:27]([C:26]1[CH:28]=[CH:29][C:23]([O:22][CH2:21][CH2:20][O:19][CH2:18][CH2:17][O:16][CH2:15][CH2:14][O:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH:2]2[CH2:3][CH2:4][CH2:5][CH2:6][O:1]2)=[CH:24][CH:25]=1)=[C:30]=[O:31]

参加物

3

反応物 2

HCID 19083224Phosgen tolueneHCID 867098904-(14-(Tetrahydro-2H-pyran-2-yloxy)-3,6,9,12-tetraoxatetradecyloxy)aniline

生成物 1

HCID 867098892-(14-(4-Isocyanatophenoxy)-3,6,9,12-tetraoxatetradecyloxy)tetrahydro-2H-pyran

実験手順

To a stirred 0° C. solution of 29 (0.95 g, 2.30 mmol) in 5:1 DCM/TEA (30 mL) was added a 20% phosgene/toluene solution (2.43 mL, 4.59 mmol). After stirring for 3 h the reaction was concentrated under reduced pressure and carried on without further purification.

後処理

  1. concentrationwas concentrated under reduced pressure
  2. customcarried on without further purification

出典と根拠

ORDレコード
ord-f09b80b9632e437da29bd35fd46b753c
出典データセット
uspto-grants-2014_09
特許番号
US08841460B2

関連ノート

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