Methylamine → 3-[(2-chloro-4-iodophenyl)amino]-N-methylisonicotinamide
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([OH:14])=O.[CH3:19][NH2:20]>>[Cl:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([NH:20][CH3:19])=[O:14]参加物
3
実験手順
3-[(2-chloro-4-iodophenyl)amino]-N-methylisonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.32 mmol of 3-[(2-chloro-4-iodophenyl)amino]isonicotinic acid (intermediate 2) and 0.43 mmol of monomethylamine LC/MS [9.23 min; 389 (M+1)]
出典と根拠
- ORDレコード
- ord-38503d46ac664280ac0f152ab9434014
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08841459B2
反応ノート
読み込み中…